If you have a media computer or computer connected to TV, You might want to remote control your computer when you are sitting in the couch or you are playing music etc. You may want to control mouse, keyboard and any other software on your windows PC, Linux or mac using WiFi or Bluetooth.
There are several apps available in Amazon App Store that allow you to access & control your PC from a distance using WiFi. If you don’t have access to WiFi, for example when presenting a ppt, You can ue Bluetooth to connect to computer and control it.
How to control PC mouse/keyboard/software from Kindle Fire HD
1. Download & Install All in One Remote Pro server application on the computer. Make you have Java Installed on your computer. You can install Java from here.
2. Download & Install All In One Remote Pro app from Amazon AppStore on your Kindle Fire HD/2. This app costs about $1.

Make sure the application is running on the computer & connect to it from your Kindle Fire tablet. You also need to be on the same WiFi network. You can also use Bluetooth option.
You can also control media players like Windows Media Player, VLC, Winamp and play songs. You can play games using gamepad.
There are other apps like WInput, Remote Mouse
etc in the Amazon App Store.
Also read, how to transfer or sync iTunes music to Kindle Fire HD